Paul’s Second Missionary Journey

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Paul’s Second Missionary Journey
Approx. 2500 Miles – 2½ Years – AD 49 – 52
Acts – Chapters 15 vs 36 – 18 vs 22

Scripture Ref.PlaceWhat happened
ACTS – 15:35-40  AntiochDispute between Paul and Barnabas over John Mark – while Barnabas takes John Mark with him to Cyprus. Silas goes with Paul to ⇒
ACTS – 15: 41Syria and Cilicia (Turkey) Paul re-visits the regions of  Syria and Cilicia strengthening the Churches. They proceed to ⇒
ACTS – 16:1-5Derbe LystraTimothy joins Paul and Silas – the churches are strengthened and increase in number. They pass through the regions of ⇒
ACTS 16:6-8Phrygia and Galatia*  The Holy Spirit forbids them to preach in Asia, so they proceed through Mysia. They try to go into Bithyinia, but are stopped by the Holy Spirit. They proceed to  ⇒
ACTS 16: 11 **  Troas (Western Turkey)In a vision, Paul sees a man of Macedonia pleading with him to come and help them. They sail to Samothrace near to Neapolis; next day proceed to ⇒
ACTS 16:13-40    Phillipi *Lydia is converted, Paul and Silas imprisoned because a devil possessed girl is healed. The jailor is converted . An earthquake shakes the prison, releasing the prisoners – the magistrates implore Paul and Silas to leave Phillipi when they find out that they are Roman citizens. They pass though ⇒
ACTS – 17:1-9Amphipolis, Apolonia – to Thessalonica *Paul and Silas reason with the Jews in the synagogue; they are persecuted by the Jews, they  flee by night to ⇒
ACTS 17:10-14BereaFair-minded Jews in the synagogue search the Scriptures daily, receive the word readily from Paul and Barnabas; Jews from Thessalonica stir up trouble. Silas, Timothy & Luke stay, Paul travels to ⇒
ACTS 17:15-34AthensWhile he waits for Timothy and Silas, Paul disputes with the Jews in the synagogue and in the marketplace. He proclaims Christ to learned men on Mars hill (the Areopagus) – there are conversions. Paul departs to ⇒
ACTS – 18:1-18  Corinth *Paul stays with a Christian couple – Priscilla & Aquila – all tent makers.  Paul is joined by Timothy and Silas.  Crispus, the chief ruler is converted.  They stay 18 months, then travel to ⇒
ACTS 18:19-21Ephesus *Paul preaches in the synagogue. He cannot stay, as he has to go to the Feast in Jerusalem. Sails to ⇒ 
ACTS 18:22Caesarea – in SyriaPaul greets the Church in Jerusalem and returns to Antioch in Syria.

© Mark Stapleton November 2025

* Letters (epistles) were written by Paul to the Christians in these places.

** Commentators suggest that Luke joined Paul and Silas at Troas: verse 11 uses the word “we” for the first time.

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